Deuterium(D) or 2H is a naturally-occurring, stable, non-radioactive isotope of Hydrogen which is widely used for labeling. It is prepared by hydrogen–deuterium (H/D) exchange reaction using either D2 or D2O along with the catalyst.
Other than Deuterium main isotopes routinely used are 1H, 13C and 15N, with a more sparse use of 31P, 19F and 17O.
Isotope labeled compounds are used in chemistry and biochemistry to understand reaction mechanisms, metabolic pathway, metabolic transformations and interactions because they have different masses and can be detected by Mass Spectroscopy(MS) and different vibration modes which can be detected by IR and NMR.
Deuterium labeled standards are broadly employed in organic chemistry, organometallic chemistry, enzymology, spectroscopy, pharmacology, and many other fields
Applications are:
- Study of reaction mechanism
- Study Biosynthetic pathway
- Internal standard for Mass Spectroscopy
- Improve metabolic stability of drug
Synergy Analytical Laboratories is leading manufacturer/suppliers/exporter of Deuterium compounds and other isotope labeled compounds in India and across the world. With over 10,000 Deuterium labeled compounds available at Synergy Analytical Laboratories, we also offer pack sizes of 1mg and 10mg along with customized pack sizes.